IOWA CITY, Iowa -- Freshman Keith Duncan kicked a 33-yard field goal as time expired and Iowa stunned second-ranked Michigan 14-13 on Saturday night, damaging the Wolverines playoff hopes.Akrum Wadley had 115 yards rushing for the Hawkeyes (6-4, 4-3 Big Ten) in their first victory over a top-five team in six years.Michigan (9-1, 6-1, No. 3 CFP) appeared to have the game wrapped up on Channing Striblings interception with 1:54 left. But the Hawkeyes defense stuffed the Wolverines, and a facemask penalty put Iowa at Michigans 36 with 1:23 to go.Duncan then drilled the ball through the uprights from nearly the exact same spot where Daniel Murray hit the winner eight years ago to knock Penn State out of the national title picture.But Michigan is still very much alive, in part because No. 3 Clemson and No. 4 Washington also lost Saturday.PITTSBURGH 43, NO. 3 CLEMSON 42CLEMSON, S.C. -- Chris Blewitt made a 48-yard field goal with 6 seconds left and Pittsburgh stunned Clemson 43-42, spoiling a record-setting day for quarterback Deshaun Watson and complicating the Tigers path back to the College Football Playoff.It was the biggest win for the Panthers (5-4, 3-4 Atlantic Coast Conference) since knocking off then-No. 2 West Virginia 13-9 in 2007.Watson threw for an ACC-record 580 yards and three touchdowns. But his third interception gave Pitt the chance to crawl back from a 42-34 deficit. After Saleem Brightwells pick and 70-yard return, James Conner finished the drive with a 20-yard TD run.The Panthers defense, which gave up 630 yards, stopped Wayne Gallman short on third and fourth down to take the ball with 58 seconds left. Two passes to Scott Orndoff put Pitt within range and Blewitt nailed the kick to send the Panthers into a frenzy.SOUTHERN CALIFORNIA 26, NO. 4 WASHINGTON 13SEATTLE -- Sam Darnold threw for 287 yards and two touchdowns and Southern California upset Washington, snapping the Huskies 12-game winning streak and damaging their College Football Playoff hopes.Darnold was outstanding against one of the top defenses in the Pac-12, showing why USC has surged since he became the starter. Darnolds lofted pass over linebacker D.J. Beavers and into the arms of tight end Daniel Imatorbhebhe for an 8-yard touchdown strike in the opening moments of the fourth quarter gave USC an 11-point lead that Washington (9-1, 6-1 Pac-12, No. 4 CFP) couldnt overcome.Ronald Jones II added 93 yards rushing and a touchdown. USC (7-3, 6-2, No. 20 CFP) won its sixth straight. The Trojans also kept alive their slim hopes of winning the Pac-12 South.Darreus Rogers had six catches for 84 yards and a touchdown, while Imatorbhebhe added five catches for 78 yards. Washington lost starting middle linebacker Azeem Victor in the second quarter to a lower right leg injury that required an air cast and a cart to take the Huskies leading tackler off the field. But his absence was felt more in the pass game where USC exploited the middle of the field.Washington quarterback Jake Browning was 17 of 36 for 259 yards, including a 70-yard scoring pass to John Ross. Ross finished with eight catches for 154 yards.NO. 1 ALABAMA 51, MISSISSIPPI STATE 3TUSCALOOSA, Ala. -- Jalen Hurts passed for career highs of 347 yards and four touchdowns and ran for 100 yards in less than three quarters in Alabama victory over Mississippi State.The freshman quarterbacks prolific performance wiped out any concerns that the Crimson Tide (10-0, 7-0 Southeastern Conference, No. 1 CFP) would have a letdown after a bruising win at No. 19 LSU. Instead, Hurts turned in his best game and the defense denied Mississippi State (4-6, 2-4) the end zone on nine trips across midfield.Hurts is the first Alabama player to have 300 yards passing and 100 yards rushing in the same game.Hurts completed 28 of 37 passes and rushed for a fifth touchdown before being replaced by Cooper Bateman late in the third quarter. The career performance was marred by an interception and fumble, but the Tides dominating defense made sure the miscues didnt matter too much.ArDarius Stewart was the biggest beneficiary of the passing revival, scoring three touchdowns. Stewart gained 156 yards on eight catches, including a 67-yard sprint on a jet sweep.NO. 5 LOUISVILLE 44, WAKE FOREST 12LOUISVILLE, Ky. -- Brandon Radcliff ran for three touchdowns during Louisvilles 41-point second half, and the Cardinals routed Wake Forest despite a relatively quiet night from Lamar Jackson.Louisville (9-1, 7-1 Atlantic Coast Conference, No. 6 CFP) trailed 12-0 behind three lost first-half fumbles before shutting down the Demon Deacons, holding them to just 37 yards after halftime. That opened the door for Radcliff to run for 141 yards and TDs of 55, 7 and 19 yards.Jackson appeared headed for his first scoreless game since Nov. 14 against Virginia before completing a 2-yard pass to Cole Hikutini with 4:05 left for one of Louisvilles five touchdowns in the fourth quarter. Ronald Walker also had a 31-yard interception return for a TD in the final period, and Malik Williams added a 2-yard run with 50 seconds left.Jackson rushed for a game-high 153 yards on 22 carries, but he was held to 145 yards passing.NO. 6 OHIO STATE 62, MARYLAND 3COLLEGE PARK, Md. -- J.T. Barrett accounted for four touchdowns, Curtis Samuel scored three TDs and Ohio State enjoyed another lopsided victory.Coming off a 62-3 roput of then-No. 10 Nebraska, the Buckeyes led 21-3 after the first quarter and 45-3 at halftime. Unlike last week, this blowout was no surprise because it came against a struggling team with quarterback issues and a porous defense.Ohio State (9-1, 6-1 Big Ten, No. 5 CFP) has won three straight to remain in contention for the Big Ten title and, more importantly, a berth in the College Football Playoff. Maryland (5-5, 2-5) has been outscored 121-6 over the last two weeks and given up 163 points during its three-game losing streak.With Barrett and Samuel leading the way, the Buckeyes eliminated any potential drama by scoring touchdowns on three of their four possessions in the first quarter.NO. 7 WISCONSIN 48, ILLINOIS 3MADISON, Wis. -- Corey Clement ran for 123 yards and three touchdowns and Wisconsin intercepted four of Illinois quarterback Jeff George Jr.s passes.Dare Ogunbowale added 103 yards on seven carries for the Badgers (8-2, 5-2 Big Ten, No. 7 CFP). They rushed for a season-high 363 yards as a team.Safety Leo Musso had two interceptions for the Badgers.Wisconsin led by 18 after the first quarter with two scores from Clement, and 31-3 at the half on a homecoming weekend at Camp Randall Stadium. Illinois (3-7, 2-5) had just 60 yards and three first downs in the second half.GEORGIA 13, NO. 8 AUBURN 7ATHENS, Ga. -- Rodrigo Blankenship kicked two fourth-quarter field goals and Georgias defense shut down Auburn in the second half.The loss ended Auburns Southeastern Conference championship hopes and knocked the Tigers (7-3, 5-2 SEC, No. 9 CFP) out of consideration for a spot in the playoff.The Tigers couldnt overcome the loss of star running back Kamryn Pettway, the nations No. 4 rusher who hurt his left leg on a long run in last week against Vanderbilt.Auburn was held to 32 yards in the second half and 164 overall.Georgia (6-4, 4-4) earned its biggest win under first-year coach Kirby Smart. After Blankenships 21-yard field goal with 2:25 remaining, Auburn was stopped on four downs, triggering a celebration in the stands and on Georgias sideline.NO. 9 OKLAHOMA 45, NO. 25 BAYLOR 24NORMAN, Okla. -- Baker Mayfield passed for 300 yards and two touchdowns and ran for another score to help Oklahoma beat Baylor.The Sooners (8-2, 7-0 Big 12, No. 11 CFP) won their seventh in a row overall and 15th straight in Big 12 play. Joe Mixon had 187 yards from scrimmage and Samaje Perine ran for 100 yards and two touchdowns after missing three games with a pulled muscle in his right leg for Oklahoma .Baylor (6-3, 3-3) had hoped to bounce back after a 62-22 loss to TCU. Instead, the Bears are on their first three-game losing streak since the middle of the 2012 season.Baylor quarterback Seth Russell severely dislocated his left ankle and was carted off the field with 5:48 left in the third quarter.MISSISSIPPI 29, NO. 10 TEXAS A&M 28COLLEGE STATION, Texas -- Shea Patterson threw for 338 yards and two touchdowns in his debut and Gary Wunderlich made a 39-yard field goal with 37 seconds left to lift Mississippi past Texas A&M.The Rebels pulled the redshirt off Patterson, the highly regarded recruit, to start in place of Chad Kelly, who suffered a season-ending knee injury last week.Mississippi (5-5, 2-4 Southeastern Conference) trailed by 15 entering the fourth quarter before Patterson got going.A 13-yard touchdown reception by Josh Reynolds put A&M up 28-19. Patterson then connected with Van Jefferson on a 32-yard reception for his second TD pass of the quarter to cut the lead to 28-26 with 5:17 remaining. A&M (7-3, 4-3) had to punt and Patterson moved the offense into position for Wunderlichs game-winning field goal.The Aggies had a chance to win it late, but Jake Hubenaks pass was intercepted by Deontay Anderson to secure the victory. Hubenak was making his first start this season in place of Trevor Knight, who injured his shoulder last week.NO. 11 WEST VIRGINIA 24, TEXAS 20AUSTIN, Texas -- Kennedy McCoy ran for two touchdowns and West Virginias defense withstood a final pass attempt into the end zone to hold off Texas.Skyler Howard passed for 269 yards and a touchdown to help West Virginia (8-1, 5-1 Big 12, No. 16 CFP) keep its conference title hopes alive. The Mountaineers gave up 167 yards rushing to DOnta Foreman but kept him out of the the end zone.Texas (5-5, 3-4) had one last shot to win on the final play when Shane Buechele lobbed a pass high into the end zone but it floated too far and incomplete. Game officials checked replay to see if West Virginia had too many players on the field, but confirmed the play and the game was over.NO. 12 PENN STATE 45, INDIANA 31BLOOMINGTON, Ind. -- Saquon Barkley ran for two go-ahead touchdowns in the fourth quarter, helping Penn State beat Indiana.Barkley was held to 20 yards on 20 carries though the first three quarters. But the Big Tens top rusher stepped up in the final period, and the Nittany Lions (8-2, 6-1, No. 10 CFP) keep pace with No. 2 Michigan in the East Division with their sixth consecutive victory.First, Barkley found a hole for a 4-yard TD run that made it 28-24. After Indiana regained the lead on Richard Lagows 40-yard touchdown pass to Nick Westbrook, Barkley ran over a defender for a 2-yard score with 3:58 left. Penn State sealed the win with a 9-yard fumble return for a TD with 29 seconds left.Indiana (5-5, 3-4) had won two in a row.NO. 16 COLORADO 49, ARIZONA 24TUCSON, Ariz. -- Sefo Liufau passed for three touchdowns and ran for another, helping Colorado roll over Arizona for its first four-game winning streak in 14 years.Colorado (8-2, 7-1 Pac-12, No. 12 CFP) had no trouble with the banged-up Wildcats, finding the offensive rhythm that had been missing the past two weeks.Liufau was sharp after being banged up against UCLA, hitting 19 of 27 passes for 213 yards, including two touchdowns to Shay Fields. Liufau also ran for a 2-yard score.Phillip Lindsay ran for 119 yards and three touchdowns, helping the Buffaloes to their best start since opening the 2001 season 8-2.Arizona (2-8, 0-7) is in the midst of its first seven-game losing streak since 2004.NO. 17 OKLAHOMA STATE 45, TEXAS TECH 44STILLWATER, Okla. -- Clayton Hatfield missed the extra point after Quinton Whites 1-yard scoring run for Texas Tech with 1:39 left, and Oklahoma State escaped with the victory.Texas Tech (4-6, 2-5 Big 12) appeared to have overcome a 10-point deficit when White spun into the end zone on third-and-goal, but Hatfields kick sailed wide right, leaving the Red Raiders down by one.After Oklahoma State (8-2, 6-1, No. 13 CFP) recovered the onside kick attempt, the Cowboys marched quickly into the red zone, and resisted Techs attempts to let them score before running out the clock.Mason Rudolph threw for 395 yards and two touchdowns on 20-of-28 passing for Oklahoma State, and Justice Hill had 126 yards and a touchdown on 18 carries. James Washington registered six receptions for 158 yards, including an 82-yard TD catch with 6 seconds left in the third quarter that put the Cowboys ahead 45-35. Techs Patrick Mahomes completed 34 of 51 passes for 344 yards and three touchdownsGEORGIA TECH 30, NO. 18 VIRGINIA TECH 20BLACKSBURG, Va. -- Georgia Tech backup quarterback Matthew Jordan rushed for 121 yards and two touchdowns to lead the Yellow Jackets past Virginia Tech.Jordan made his first career start in place of an injured Justin Thomas, helping make the Yellow Jackets (6-4, 3-4 Atlantic Coast Conference) bowl eligible. He repeatedly gashed the Hokies defense, carrying 32 times and scoring on runs of 53 and 3 yards.Marcus Marshall added 143 yards rushing and a score.Virginia Tech (7-3, 5-2, No. 14 CFP) missed a chance to clinch the ACCs Coastal Division.NO. 19 LSU 38, ARKANSAS 10FAYETTEVILLE, Ark. -- Derrius Guice rushed for a career-high 252 yards, Leonard Fournette added three touchdowns and LSU improved to 4-1 under interim coach Ed Orgeron.LSU (6-3, 4-2 Southeastern Conference, No. 24 CFP) was coming off a 10-0 loss to No. 1 Alabama.Guice rushed for two touchdowns on 21 carries, and his 96-yard touchdown run in the fourth quarter was the longest in school history. Fournette scored on runs of 7, 7 and 3 yards, and had 98 yards rushing.The Tigers outgained Arkansas (6-4, 2-4, No. 25 CFP) 547-291 in total yardage, and LSU quarterback Danny Etling finished 10-of-16 passing for 157 yards.NO. 21 NEBRASKA 24, MINNESOTA 17LINCOLN, Neb. -- Tommy Armstrong Jr. led a 91-yard tiebreaking touchdown drive after being helped off the field with an ankle injury the previous series, and Kieron Williams interception with 1:29 left secured Nebraskas victory.Armstrong, knocked unconscious in last weeks loss at Ohio State, was cleared to start against the Gophers and was playing one of his best games in weeks when he injured his left ankle on a quarterback sneak late in the third quarter.He came back to loud cheers on the Cornhuskers early in the fourth and scored the go-ahead touchdown on a 13-yard run with 7:17 left. He stumbled into the end zone, came up hobbling again and was carried to the sideline by two offensive linemen.Williams intercepted Mitch Leidners tipped pass after the Gophers had driven to the Nebraska 17, and backup quarterback Ryker Fyfe took the final snaps as the Huskers (8-2, 5-2 Big Ten) won for the first time in three games and a week after getting humiliated 62-3 at Ohio State.Minnesota (7-3, 4-3) had its four-game win streak ended.NO. 22 FLORIDA 20, SOUTH CAROLINA 7GAINESVILLE, Fla. -- Austin Appleby threw two touchdown passes, Jordan Scarlett ran for a career-high 134 yards and Florida beat South Carolina and former coach Will Muschamp, moving closer to clinching the Southeastern Conferences Eastern Division.The banged-up Gators (7-2, 5-2) can secure a spot in the league title game by winning at LSU next week. It might be a long shot given Floridas injury situation.Coach Jim McElwain lost nine starters the last two weeks, including four against the Gamecocks (5-5, 3-5). Safety Marcus Maye (shoulder), defensive end Bryan Cox Jr. (ankle), center Tyler Jordan (ankle) and right tackle David Sharpe (leg) all left the game and did not return.NO. 23 WASHINGTON STATE 56, CALIFORNIA 21PULLMAN, Wash. -- Luke Falk threw five touchdown passes, including three to River Cracraft, and Washington State beat California for its eighth consecutive victory.The surging Cougars (8-2, 7-0 Pac-12, No. 23 CFP) have their longest winning streak since 1930 and are on a surprising quest for a Pac-12 championship.Davis Webb threw for 425 yards and three touchdowns for Cal (4-6, 2-5), which has lost three straight games and is struggling to keep its bowl hopes alive.Cracraft caught nine passes for 87 yards before leaving midway through the third quarter with a leg injury. Falk completed 36 of 50 passes for 373 yards with one interception.NO. 24 BOISE ST 52, HAWAII 16HONOLULU -- Brett Rypien passed for 338 yards and four touchdowns for Boise State.The Broncos (9-1, 5-1 Mountain West, No. 22 CFP) racked up a season-high 603 yards of total offense, 403 of them coming before halftime. Jeremy Nichols, the nations leading scorer, ran for 153 yards on 16 carries and scored on runs of 36 and 5 yards. Rypien finished 18-of-22 passing.Cedrick Wilson had seven receptions and 141 yards with a touchdown, and Thomas Sperbeck added five grabs for 114 yards and two scores. Paul Harris ran for 145 yards for Hawaii (4-7, 3-4).---More AP college football: www.collegefootball.ap.org and http://www.twitter.com/AP-Top25 http://www.saintsrookiestore.com/Saints-Marshon-Lattimore-Jersey/ . 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