30th October 2018 – Kaposi Sarcoma is a tumor caused by infection with human herpes virus 8. It is also known as Kaposi sarcoma-associated herpes virus or KS agent. It becomes widely known as one of the AIDS-defining illnesses. It is viral infection. There is a widespread lack of awareness of this even among persons at risk for HHV-8 infection. Kaposi sarcoma (KS) is a systemic disease with cutaneous lesions with or without internal involvement. The Kaposi sarcoma (KS) is considered to be an AIDS-defining disease; indicating that patients with KS go on to develop AIDS. The incidence of Kaposi sarcoma was reportedly high in homosexual men with HIV. Kaposi Sarcoma is different from the other cancers in that lesions may be in more than one place in the body at the same time. These affected areas are called lesions. The skin lesions of KS most often appear on the legs or face and may cause it to swell painfully.
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KS can cause serious problems or even become life treating when the lesions are in the lungs, liver, or in digestive tract. The means that the when KS occurs in someone is infected with HIV. Chemotherapy wholesale nike air vapormax flyknit , immunotherapy, and antiretroviral therapy (HAART) are the key treatment methods for Kaposi sarcoma. The HAART therapy emerged as the leading segment owing to the high incidence of AIDS-related Kaposi sarcoma globally. HAART therapy includes the combination of reverse transcriptase (RT) inhibitors, fusion inhibitors, and protease inhibitors. Chemotherapy is likely to grow at the fastest pace during the forecast period due to the high cost of the treatment and the increasing adoption by immunocompentent patients.
The leading chemotherapy drugs include paclitaxel, liposomal doxorubicin and daunorubicin wholesale nike vapormax flyknit 2.0 , bleomicin and vincristine. Immunotherapy consists of interferon alfa; which is the first biological drug approved by the FDA to the treatment of Kaposi sarcoma. Patients with good immune functions show effectiveness. However, immune compromised patients rarely respond to this therapy. The therapy accounted for the least share in the global market. Kaposi Sarcoma Market by Type of Treatment is segmented into Chemotherapy, Liposomal Anthracyclines, Alkaloids, Immunotherapy wholesale nike vapormax flyknit , HAART. Kaposi Sarcoma Market by Distribution Channel is segmented into Hospitals, Cancer Research Institutes, Multispecialty Clinics, Ambulatory Surgical Centers.
Kaposi Sarcoma Market by Geographical Region is segmented into North America, Latin America wholesale nike vapormax 2.0 , Europe, Asia-Pacific, and the Middle East and Africa. North America contributed to the major share in the Kaposi sarcoma market in 2015. Due to the presence of key market players and the increasing cost of drugs; the growth of the market is also driven by the easy availability of drugs and a high diagnosis rate of the malignancy. The high cost of the therapy is a deterrent to patients in developing regions such as Asia Pacific and the Middle East and Africa and this limits its adoption. A limited number of approved biologics is also a prominent factor restraining the growth of the immunotherapy segment. The Middle East and Africa are expected to expand at the highest CAGR during the forecast period owing to the high incidence and prevalence of KS in Eastern Africa. The trend is consistent with the geographic variations of the HIVAIDS epidemic. The key players include Aphios Corporation, AstraZeneca Plc, Biogenomics Limited wholesale nike air vapormax , and CytRx Corporation. Eli Lilly and Co., Hoffman-La Roche, Inc., GlaxoSmithKline plc, Johnson & Johnson wholesale nike vapormax cheap , Pfizer, Inc., and Schering Plough Corporation (Merck & Co., Inc.).
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Paris on Monday resorted to drastic measures to curb soaring pollution levels by forcing all cars with number plates ending in even numbers off the road for the first time in two decades.
Around 700 police officers were deployed to man 60 checkpoints around the French capital to ensure that only cars with number plates ending in odd numbers were out on the streets.
Public transport has been free since the weekend to persuade Parisians to leave their cars at home, and the state railway company SNCF warned on its website of packed suburban trains at peak hours due to the extreme measure.
"It is sure we will have more clients today," a delighted taxi driver told AFP.
"There are people who take their car because they don't want to be pressed up against others in the metro. Today they will take a taxi."
The restrictions came into force across Paris and 22 surrounding areas from 5:30 am (0430 GMT).
They will be reviewed on a daily basis, with odd numbers potentially banned on Tuesday if an extension is deemed necessary.